Costas Pantelides is currently the Managing Director of Process Systems Enterprise and a professor of Chemical Engineering at Imperial College London. Costas holds BSc and PhD degrees from Imperial College, and an MS degree from the Massachusetts Institute of Technology. Working in the area of process modeling technology for more than 3 decades, he has played a leading role in the design and development of the gPROMS and SPEEDUP software. A key focus of his current activities is the role that deep knowledge, captured and encoded in mathematical models, can play in the ongoing digital transformation of the process industries, and the architecture and design of general software platforms to support this. His research at Imperial is concerned with computational chemistry, with particular focus on the ab initio prediction of crystal structures. Costas’ contributions have been honored by several major awards including the 2007 Royal Academy of Engineering MacRobert Award, the UK's most prestigious prize for engineering innovation, the 2016 Sargent Medal of the UK Institution of Chemical Engineers, and a doctorate Honoris Causa from the Technical University of Dortmund in 2019. He is a Fellow of the UK Institution of Chemical Engineers and of the Royal Academy of Engineering.